This paper describes the areal distribution of fecal coliform densities within the stream system of the South Platte River basin in Colorado. Low densities, e.g., 0 to 99 fecal coliforms per 100 ml, were found in mountain streams, while higher densities, e.g., 10000 to 100000 and above were found in plains streams. About 49 % of the plains stations and 3 % of the mountain stations were not in compliance with the Colorado secondary contact recreation standard of 2000 fecal coliforms per 100 ml. The higher fecal coliform densities were associated with discharges from wastewater treatment plants. This is significant from a public health standpoint since the tainted waters are spread throughout the South Platte basin to irrigated lands via streams, canals, and reservoirs. Because of current federal and state policy encouraging land treatment and reuse, such practice should be reviewed with respect to compliance with proposed fecal coliform standards, and whether such standards should be adopted.