descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Other literature type 01 Jan 2013 English Publisher:Springer Netherlands

Authors: STAIBANO, STEFANIA;

doi: 10.1007/978-94-007-7149-9_7

handle: 11588/643572

Resistance to Castration – Resistance to Drugs

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Abstract

Up to 70 % of newly diagnosed patients with advanced prostate cancer (PCa) will progress to castration-resistant prostate cancer (CRPC) and, in most cases (from 50 to 70 %), will develop hematogenous bone metastasis. Once PCa cells spread to the skeleton, cancer-related death becomes inevitable, with a death burden of more than 28,000 cases in 2012, in the United States (Semenas et al, Curr Drug Target, 13(10):1308–1323, 2012).

Related Organizations

University Federico II of Naples
Italy

Keywords

Medicine (all)

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