It is now several decades that diverse surgical and pharmacological treatments have been employed to prevent and/or ameliorate the sensory motor deficits which ensue an injury to the spinal cord. The restoration of impaired histological and physiologic parameters by compounds which are membrane stabilizers, antiinflammatory, and antioxidant, and which increase the regional blood flow such as methylprednisolone sodium succinate, naloxone, hypothalamic thyrotropic releasing hormone, and epsilonaminocaproic acid suggest that the changes seen after trauma may be secondary to a marked membrane disorganization and dysfunction. The changes in the phospholipid-dependent, membrane bound enzyme monoamine oxidase and the formation of microglobules and non-cellular material on the endothelial lining are early signs of membrane pathology (1).