antisense oligonucleotides (AS-ODNs)

Name: antisense oligonucleotides (AS-ODNs)
Creator: Gerhard Nahler
Keywords: 3. Good health

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Other literature type 01 Jan 2009 English Publisher:Springer Vienna

Authors: Gerhard Nahler;

doi: 10.1007/978-3-211-89836-9_77

antisense oligonucleotides (AS-ODNs)

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Abstract

Class of new therapeutics planned for the treatment of viral infections, autoimmune disease, endocrine disease and cancers; AS-ODNs are small synthetic molecules of single-stranded DNA that suppress gene expression by binding to RNA templates in a sequence-specific manner, thus suppressing gene expression, mRNA translation and therefore the production of disease-causing proteins; → see gene therapy, ribozyme.

Related Organizations

Clinical Investigation Support (Austria)
Austria

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