descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1982 English Publisher:Elsevier BVJournal:Journal of Pharmaceutical Sciences, volume 71, pages 1,049-1,052 (issn: 0022-3549,

Authors: Paul E. Flinn; Ross D. Kirchhoefer; Everett H. Jefferson;

doi: 10.1002/jps.2600710923

pmid: 7131273

Aspirin—A National Survey V: Determination of Aspirin and Impurities in Enteric Coated Tablets and Suppository Formulations and In Vitro Dissolution of Enteric Coated Tablets

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Abstract

The results of a national survey on the quality of enteric coated aspirin tablets and aspirin suppositories are presented. The tablets were analyzed for strength, salicylic acid content, in vitro dissolution rate, and related aspirin impurities. The suppositories were analyzed for strength and salicylic acid content. The methods of analysis and validation of data are also presented.

Related Organizations

United States Food and Drug Administration
United States

Keywords

Aspirin, Solubility, Suppositories, Chromatography, Thin Layer, Tablets, Enteric-Coated, Drug Contamination, Salicylic Acid, Salicylates, United States

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