Lack of Marseillevirus DNA in immunocompetent and immunocompromised Italian patients
Copyright policy )Lack of Marseillevirus DNA in immunocompetent and immunocompromised Italian patients
AbstractMarseilleviridae is a family of viruses which have only been propagated in acanthamoeba. Marseillevirus sequences have been recently detected in different human matrices by viral metagenomics. Single‐center studies worldwide have estimated a low prevalence of marseillevirus both in symptomatic patients and in healthy donors but, to date, no informations are available on the prevalence of this giant virus in Italy. By a polymerase chain reaction targeting the ORF152 viral sequence, we tested sera from 197 immunosuppressed patients and 285 healthy donors, and 63 and 30 respiratory and cerebrospinal fluid samples, respectively, of patients with various clinical conditions and referring the Virology Division for diagnostic purposes. We observed no evidence of Marseillevirus DNA in all 575 samples tested. Marseillevirus probably does not cause infection in human.
Adult, Male, giant virus; healthy donors; immunocompromised patients; Italian population; Marseilleviridae; Marseillevirus; Adult; Aged; Blood; Cerebrospinal Fluid; Child; Child, Preschool; DNA, Viral; Female; Humans; Immunocompetence; Immunocompromised Host; Italy; Male; Middle Aged; Mimiviridae; Polymerase Chain Reaction; Respiratory System, Respiratory System, Middle Aged, Polymerase Chain Reaction, Immunocompromised Host, Blood, giant virus; healthy donors; immunocompromised patients; Italian population; Marseilleviridae; Marseillevirus, Italy, Child, Preschool, DNA, Viral, Humans, Female, Child, Mimiviridae, Immunocompetence, Aged, Cerebrospinal Fluid
Adult, Male, giant virus; healthy donors; immunocompromised patients; Italian population; Marseilleviridae; Marseillevirus; Adult; Aged; Blood; Cerebrospinal Fluid; Child; Child, Preschool; DNA, Viral; Female; Humans; Immunocompetence; Immunocompromised Host; Italy; Male; Middle Aged; Mimiviridae; Polymerase Chain Reaction; Respiratory System, Respiratory System, Middle Aged, Polymerase Chain Reaction, Immunocompromised Host, Blood, giant virus; healthy donors; immunocompromised patients; Italian population; Marseilleviridae; Marseillevirus, Italy, Child, Preschool, DNA, Viral, Humans, Female, Child, Mimiviridae, Immunocompetence, Aged, Cerebrospinal Fluid
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