Regression analysis of ames test data

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1981 English Publisher:WileyJournal:Environmental Mutagenesis, volume 3, pages 575-586 (issn: 0192-2521, eissn: 1930-238X,

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Authors: L E, Myers; N H, Sexton; L I, Southerland; T J, Wolff;

doi: 10.1002/em.2860030509

pmid: 7026227

Regression analysis of ames test data

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Abstract

AbstractWeighted least squares estimation is used for fitting nonlinear models to Ames test data. The models are biologically plausible, incorporating mutagenicity, toxicity, and/or saturation. Regressions are weighted to compensate for variance that changes with mean and to attain outlier resistance.

Related Organizations

RTI International
United States
Research Triangle Park Foundation
United States

Keywords

Salmonella typhimurium, Kinetics, Mutagenicity Tests, Mutation, Statistics as Topic, Regression Analysis, Mutagens

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