AbstractThe association of intracranial aneurysms and sickle cell disease (SCD) has been described in the English‐language literature. Treatment strategies have included angiography and craniotomy. However, with advancement of non‐operative interventions, much controversy surrounds the treatment of these patients. Endovascular embolization has been used in many patients with cerebral aneurysms, but it had been reported in the literature in only two sickle cell patients. The authors present a case of endovascular embolization of multiple intracranial aneurysms in a patient with sickle cell anemia with good outcome. Am. J. Hematol. 76:83–84, 2004. © 2004 Wiley‐Liss, Inc.