Hemostatic Multilayer Coatings

descriptionPublicationkeyboard_double_arrow_right Article 27 Dec 2011 English Publisher:WileyJournal:Advanced Materials, volume 24, pages 492-496 (issn: 0935-9648, eissn: 1521-4095,

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Authors: Anita, Shukla; Jean C, Fang; Sravanthi, Puranam; Flemming R, Jensen; Paula T, Hammond;

doi: 10.1002/adma.201103794

pmid: 22223363

Hemostatic Multilayer Coatings

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Abstract

Spray layer-by-layer assembly is used to create hemostatic films containing thrombin and tannic acid. The spray assembly technique enables coating of porous and absorbent commercial gelatin sponges with these films. Coated sponges are able to promote instantaneous hemostasis in a porcine spleen bleeding model.

Related Organizations

Ferrosan Medical Devices (Denmark)
Denmark
Koch Institute for Integrative Cancer Research At MIT
United States
Massachusetts Institute of Technology
United States

Keywords

Hemostasis, Swine, Static Electricity, Thrombin, Polyphenols, Water, Hydrogen Bonding, Hemostatics, Animals, Gelatin, Tannins

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