Experimental Autoimmune Encephalomyelitis in the Rat
Copyright policy )Experimental Autoimmune Encephalomyelitis in the Rat
AbstractThis unit details the materials and methods required for both active induction and adoptive transfer of experimental autoimmune encephalomyelitis (EAE) in the SJL mouse strain using intact proteins or peptides from the two major myelin proteins: proteolipid protein (PLP) and myelin basic protein (MBP). Detailed materials and methods required for the purification of both PLP and MBP are also described. Modifications of the specified protocols may be necessary for efficient induction of active or adoptive EAE in other mouse strains.
- Wayne State College United States
- Wayne State University United States
Encephalomyelitis, Autoimmune, Experimental, Species Specificity, T-Lymphocytes, Guinea Pigs, Animals, Myelin Basic Protein, Rats, Inbred Strains, Disease Susceptibility, Rats
Encephalomyelitis, Autoimmune, Experimental, Species Specificity, T-Lymphocytes, Guinea Pigs, Animals, Myelin Basic Protein, Rats, Inbred Strains, Disease Susceptibility, Rats
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