[107-30-2] C2H5ClO (MW 80.51) InChI = 1S/C2H5ClO/c1-4-2-3/h2H2,1H3 InChIKey = XJUZRXYOEPSWMB-UHFFFAOYSA-N (used for the protection of alcohols, phenols, acids, amines, β-keto esters and thiols. A one-carbon synthon for alkylation of aromatics and active methylene derivatives) Alternate Names: methoxymethyl chloride; MOMCl. Physical Data: bp 55–57 °C; d 1.060 g cm−3. Solubility: sol nearly all organic solvents. Form Supplied in: available as a technical grade liquid. Preparative Methods: besides the original method2 which uses HCl, formalin, and methanol, MOMCl can be prepared from methoxyacetic acid3 or methylal (Dimethoxymethane).4 Handling, Storage, and Precautions: MOMCl is an OSHA-regulated carcinogen and depending on the method of preparation may contain bis(chloromethyl) ether, which is a more potent carcinogen. This reagent should be handled in a fume hood.