publication . Other literature type . Article . 2018

Association of Proton Pump Inhibitors With Hospitalization Risk in Children With Oropharyngeal Dysphagia

Daniel R. Duncan; Paul Mitchell; Kara Larson; Maireade E. McSweeney; Rachel Rosen;
Open Access English
  • Published: 11 Oct 2018
  • Publisher: American Medical Association
Abstract
Importance Proton pump inhibitors (PPI) are commonly prescribed to children with oropharyngeal dysphagia and resultant aspiration based on the assumption that these patients are at greater risk for reflux-related lung disease. There is little data to support this approach and the potential risk for increased infections in children treated with PPI may outweigh any potential benefit. Objective The aim of this study was to determine if there is an association between hospitalization risk in pediatric patients with oropharyngeal dysphagia and treatment with PPI. Design, Setting, and Participants We performed a retrospective cohort study to compare the frequency and...
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free text keywords: Original Investigation, Surgery, Otorhinolaryngology, Rate ratio, Hazard ratio, Retrospective cohort study, Correlation and dependence, Internal medicine, medicine.medical_specialty, medicine, Abnormal results, Enteral tubes, Pulmonary aspiration, medicine.disease, Oropharyngeal dysphagia, medicine.symptom, business.industry, business
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