To the Editor:— On Sept. 1, 1956, four children of a family developed diarrhea and vomiting. Three of them recovered after seven days. The fourth sibling continued having diarrhea and anorexia. About 14 days after this illness began, the mother noted that he was pale and that he had some bluish spots on the skin. Seventeen days after the illness, examination disclosed that he had generalized petechiae and ecchymosis and a markedly enlarged liver and spleen, a hemoglobin level of 5 Gm. per 100 cc., and a white blood cell count of 70,400 per cubic millimeter with no polymorphonuclear cells and 100% large lymphoblasts. Accordingly, a diagnosis of lymphoid leukemia was made, and the child was treated with blood transfusions, aminopterin sodium, mercaptopurine, and prednisolone. On Nov. 11, he had a remission, after 10 days of therapy. During this remission bone marrow examination showed no evidence of leukemia. On Jan.