As glioma of the retina is not commonly met with, particularly in private practice, I venture to report the following case. More than a year ago, through the courtesy of Dr. P. J. Kline, of Portsmouth, Ohio, a 14-months-old girl was brought to me for treatment of the right eye. The parents stated that the eye did not seem natural in appearance at birth, though marked signs of disease did not present themselves until the fourth month, when a whitish reflex was visible through the pupil, and later the eye increased in size, became inflamed and painful. On examination, it was found to be considerably larger than its fellow, and the ocular and palpebral conjunctivae were congested; a well-marked pericorneal zone was evident. The cornea was clear and measured 12 mm. in the vertical meridian, and 13 mm. in the horizontal. The pupil was 5 mm. in diameter, and fixed.