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Nasopharyngeal Carcinomas in Children

Authors: Don K. Weaver; John G. Batsakis; Ronald H. Nishiyama;

Nasopharyngeal Carcinomas in Children

Abstract

MALIGNANT neoplasms of the nasopharynx are uncommon in children. In Dargeon's review of 506 cases of childhood malignancies, only 27 were primary in the nasopharynx.1 In order of incidence, nasopharyngeal malignant neoplasms ranked behind neoplasms of bone, reticuloendothelial system, soft tissue, the eye and orbit, and the genitourinary tract. Epithelial malignancies occurring during childhood are greatly outnumbered by neoplasms of other tissues. Together with the gliomas and neuroblastomas, carcinomas comprise an estimated 29% of all malignant neoplasms of childhood. Sarcomas, lymphomas, and the leukemias account for 71%.2 The nasopharynx, paradoxically, is one of the more common sites of origin of epithelial malignancy in children. Numerous single case reports attest to this observation.3-7 Clinicopathological evaluations of more than one or two patients treated at a single institution are exceptional. The largest single group of patients from one experience, prior to the present report, is the series of seven children reported by Dargeon.8 The ensuing is a clinicopathological anal¬ ysis of nine children treated at the Universi¬ ty of Michigan Medical Center.

Keywords

Male, Radiography, Carcinoma, Transitional Cell, Cobalt Isotopes, Adolescent, Child, Preschool, Carcinoma, Squamous Cell, Humans, Female, Nasopharyngeal Neoplasms, Child, Prognosis

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
19
Average
Top 10%
Average
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