In this report we shall record studies of the blood lipids in three cases of xanthoma tuberosum and in five cases of xanthoma palpebrarum or xanthelasma. This work was incited by the report of Schaaf and Werner 1 on the imbalance of the lipid constituents of the blood that they found in the aforementioned disorders. At this point we should state that we follow Bloch 2 in regarding xanthoma multiplex and xanthelasma as clinically dissimilar representatives of the same disease. This may not be current American opinion; Wile, for one, regards them as entirely different diseases. In differing from that author, we refer to the reasons given by Bloch, which are readily available and need not be repeated here, and add that Pollitzer's 3 pathologic study of xanthelasma (this appears to be the basis for the opinion that xanthelasma is an entirely different disease from xanthoma) is criticized by Gans