publication . Article . 2013

Early Diagnosis of Myocardial Infarction Using Absolute and Relative Changes in Cardiac Troponin Concentrations

Irfan Affan Bin; Reichlin Tobias R.; Twerenbold Raphael; Meister Marc; Moehring Berit; Wildi Karin; Bassetti Stefano; Zellweger Christa; Gimenez Maria Rubini; Hoeller Rebeca; ...
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  • Published: 01 Jan 2013 Journal: The American Journal of Medicine, volume 126, pages 781-78,800 (issn: 0002-9343, Copyright policy)
  • Publisher: Elsevier BV
Abstract
Background: Absolute changes in high sensitivity cardiac troponin T (hs cTnT) seem to have higher diagnostic accuracy in the early diagnosis of acute myocardial infarction compared with relative changes. It is unknown whether the same applies to high sensitivity cardiac troponin I (hs cTnI) assays and whether the combination of absolute and relative change might further increase accuracy. Methods: In a prospective international multicenter study high sensitivity cardiac troponin (hs cTn) was measured with 3 novel assays (hs cTnT Roche Diagnostics Corp Indianapolis Ind; hs cTnI Beckman Coulter Inc Brea Calif; hs cTnI Siemens Munich Germany) in a blinded fashion a...
Subjects
Medical Subject Headings: cardiovascular systemsense organs
free text keywords: General Medicine, Receiver operating characteristic, Internal medicine, medicine.medical_specialty, medicine, Cardiac troponin, business.industry, business, Confidence interval, Cardiology, Absolute Change, Multicenter study, Myocardial infarction, medicine.disease
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publication . Article . 2013

Early Diagnosis of Myocardial Infarction Using Absolute and Relative Changes in Cardiac Troponin Concentrations

Irfan Affan Bin; Reichlin Tobias R.; Twerenbold Raphael; Meister Marc; Moehring Berit; Wildi Karin; Bassetti Stefano; Zellweger Christa; Gimenez Maria Rubini; Hoeller Rebeca; ...