MECAT: an ultra-fast mapping, error correction and de novo assembly tool for single-molecule sequencing reads

Preprint OPEN
Xiao, Chuan-Le; Xie, Zhi; Luo, Feng; Wang, Yan; Chen, Kai-Ning; Xie, Shang-Qian; Chen, Ying;
(2016)
  • Related identifiers: doi: 10.1101/089250
  • Subject: bepress|Life Sciences|Biology | bepress|Life Sciences|Bioinformatics

The high computational cost of current assembly methods for the long, noisy single molecular sequencing (SMS) reads has prevented them from assembling large genomes. We introduce an ultra-fast alignment method based on a novel global alignment score. For large human SMS... View more
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