Native and engineered clifednamide biosynthesis in multiple Streptomyces spp.

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Blodgett, Joshua; Ding, Edward; Qi, Yunci;

Polycyclic tetramate macrolactam (PTM) natural products are produced by actinomycetes and other bacteria. PTMs are often bioactive, and the simplicity of their biosynthetic clusters make them attractive for bioengineering. Clifednamide-type PTMs from Streptomyces sp. JV... View more
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