Complex haplotypes of metabolizing GSTM1 gene deletion harbors signatures of a selective sweep in East Asian populations

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Saitou, M.; Satta, Y.; Gokcumen, O.;

ABSTRACT The deletion of the metabolizing Glutathione S-transferase Mu 1 ( GSTM1 ) gene was previously associated with multiple cancers, metabolic and autoimmune disorders, as well as drug response. It is unusually common, with allele frequency reaching up to 75% in so... View more
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