Complex haplotypes of metabolizing GSTM1 gene deletion harbors signatures of a selective sweep in East Asian populations

Preprint English OPEN
Saitou, M.; Satta, Y.; Gokcumen, O.;
(2018)

ABSTRACT The deletion of the metabolizing Glutathione S-transferase Mu 1 ( GSTM1 ) gene was previously associated with multiple cancers, metabolic and autoimmune disorders, as well as drug response. It is unusually common, with allele frequency reaching up to 75% in so... View more
Share - Bookmark