Exploration of the role of CHRNA5-A3-B4 genotype in smoking behaviours

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Lassi, Glenda; Tan, Vanessa; Mahedy, Liam; Oliveira, Ana Sofia F.; Dyer, Maddy L.; Drax, Katie; Dawkins, Lynne; Rennard, Stephen; Matcham, James; Timpson, Nicholas J.; Eisen, Tim; Munafò, Marcus R.;
(2019)

Abstract Genome-wide association studies have identified associations between variation at rs16969968/rs1051730 in the CHRNA5–A3–B4 gene cluster and smoking related outcomes. Experiments in rodents have described the nicotinic acetylcholine receptors (nAChRs) subunit... View more
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