Development of RNAseq methodologies to profile the in vivo transcriptome of Bordetella pertussis during murine lung infection

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Wong, Ting; Hall, Jesse; Boehm, Dylan; Barbier, Mariette; Heath Damron, F.;

Abstract Bordetella pertussis is an obligate human respiratory pathogen that causes the disease whooping cough. A whole cell vaccine (DTP) was developed in the 1940s and was subsequently replaced in the 1990s with a protein-based subunit acellular vaccine (DTaP; tdap... View more
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