Exercise-Induced Muscle Damage and Hypertrophy: A Closer Look Reveals the Jury is Still Out

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Schoenfeld, Brad ; Contreras, Bret (2018)
  • Related identifiers: doi: 10.31236/OSF.IO/8A95Z
  • Subject: bepress|Life Sciences|Kinesiology | SportRxiv|Sport and Exercise Science

This letter is a response to the paper by Damas et al (2017) titled, “The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis,” which, in part, endeavored to review the role of exercise-induced muscle damage on muscle hypertrophy. We feel there are a number of issues in interpretation of research and extrapolation that preclude drawing the inference expressed in the paper that muscle damage neither explains nor potentiates increases in muscle hypertrophy. The intent of our letter is not to suggest that a causal role exists between hypertrophy and microinjury. Rather, we hope to provide balance to the evidence presented and offer the opinion that the jury is still very much out as to providing answers on the topic.
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