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Structural rearrangements of the spinal-motor segment with prolonged dynamic loads

Structural rearrangements of the spinal-motor segment with prolonged dynamic loads

Abstract

Andrii Sak & Raisa AntypovaPurpose: to study structural rearrangements of intervertebral discs and adjacent structures of the spine of rats and the possibility of their preservation under conditions of prolonged dynamic loads in the experiment. Material & Methods: study was performed in an experiment with 90 male rats of the Wistar line, using a training run in a linear treadmill for 20 and 90 days. On the histotopographic sections, after injection into the aortic arch of the animal mascara-gelatin mass, the number of capillary glomeruli in the subchondral parts of the vertebral bodies was counted. Using standard histology methods, structural changes in metaphyseal cartilages, apophyses of vertebral bodies and intervertebral discs of the lumbar spine. Results: the running regimes are defined that cause damage to various structures of the spine and, on the contrary, increase their reliability. Conclusion: it is established that with age the number of blood vessels in the bodies of the vertebrae and capillary glomeruli in their subchondral regions gradually decreases, which is accompanied by a tightening of the intervertebral disk and contiguous structures. Different in intensity and duration of physical activity cause a corresponding change in the number of blood vessels in the vertebrae and, as a consequence, the level of their blood supply.

Цель: изучить структурные перестройки межпозвоночных дисков и смежных структур позвоночника крыс и возможности их сохранения в условиях длительных динамических нагрузок в эксперименте. Материал и методы: исследование выполнено в эксперименте с 90 крысами-самцами линии Wistar, с применением тренировочного бега в линейном тредбане в течение 20 и 90 дней. На гистотопографических срезах, после инъекции в дугу аорты животных тушь-желатиновой массы, подсчитано количество капиллярных клубочков в субхондральных отделах тел позвонков. Методами стандартной гистологии изучены структурные изменения метафизарных хрящей, апофизов тел позвонков и межпозвонковых дисков поясничного отдела позвоночника. Результаты: определены режимы бега, вызывающие повреждение различных структур позвоночника и, напротив, повышающие их надежность. Выводы: установлено, что с возрастом количество кровеносных сосудов в телах позвонков и капиллярных клубочков в их субхондральных отделах постепенно снижается, что сопровождается уплотнением межпозвонкового диска и сопредельных структур. Различные по интенсивности и продолжительности физические нагрузки вызывают соответствующее изменение количества кровеносных сосудов в позвонках и, как следствие, уровня их кровоснабжения.

Keywords

running of animals in the treadmill; vertebral-motor segment; intervertebral disc; capillary glomeruli of subchondral parts of vertebral bodies, бег животных в тредбане; позвоночно-двигательный сегмент; межпозвонковый диск; капиллярные клубочки субхондральных отделов тел позвонков

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
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gold