Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behaviour of bladder cancer

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Leão, Ricardo; Price, Aryeh J.;
(2019)
  • Publisher: Wiley
  • Subject:
    mesheuropmc: congenital, hereditary, and neonatal diseases and abnormalities

In urothelial bladder cancer (UBC), risk stratification remains an important unmet need. Limitless self‐renewal, governed by TERT expression and telomerase activation, is crucial for cancer progression. Thus, telomerase activation through the interplay of mutations (TER... View more
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