publication . Preprint . Article . 2012

Oxidative Stress and Mitochondrial Injury in Chronic Multisymptom Conditions: From Gulf War Illness to Autism Spectrum Disorder

Name: Oxidative Stress and Mitochondrial Injury in Chronic Multisymptom Conditions: From Gulf War Illness to Autism Spectrum Disorder
Creator: Beatrice A. Golomb
Keywords: Immunology, Molecular Cell Biology

Beatrice A. Golomb;

Open Access

Published: 30 Jan 2012

Summary

Abstract

Background: Overlapping chronic multisymptom illnesses (CMI) include Chronic Fatigue Syndrome (CFS), fibromyalgia, irritable bowel syndrome, multiple chemical sensitivity, and Gulf War illness (GWI), and subsets of autism spectrum disorder (ASD). GWI entails a more circumscribed set of experiences that may provide insights of relevance to overlapping conditions.
Objectives: To consolidate evidence regarding a role for oxidative stress and mitochondrial dysfunction (OSMD), as primary mediators in CMI, using GWI as a departure point.
Methods: Exposure relations, character, timecourse and multiplicity of symptoms, and objective correlates of GWI a...

doi: 10.1038/npre.2012.6847.1

Subjects

free text keywords: Immunology, Molecular Cell Biology, Oxidative stress, medicine.disease_cause, medicine, Irritable bowel syndrome, medicine.disease, Fibromyalgia, business.industry, business, Multiple chemical sensitivity, Clinical psychology, Stressor, Chronic fatigue syndrome, Gulf war, Autism spectrum disorder

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