Inhibition of central insulin-receptor signaling by S961 causes hyperglycemia and glucose intolerance in rats

Preprint OPEN
Ajit Vikram; Gopabandhu Jena;
(2011)
  • Subject: Neuroscience | Pharmacology

Genetic ablation studies confirmed the role of central insulin-receptor signaling (CIRS) in fuel metabolism. However, the need to examine the role of CIRS in glucose homeostasis under normal physiological condition is indispensable, as insulin affects the neuronal growt... View more
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