publication . Article . Preprint . 2009

Antibody responses to a Cryptosporidium parvum rCP15/60 vaccine

Alexandra J. Burton; Daryl V. Nydam; Gary Jones; Jennifer Zambriski; Thomas C. Linden; Graham Cox; Randy Davis; Alicia Brown; Dwight D. Bowman;
Open Access
  • Published: 20 Nov 2009 Journal: Nature Precedings (eissn: 1756-0357, Copyright policy)
  • Publisher: Springer Science and Business Media LLC
Abstract
Cryptosporidium parvum is a zoonotic apicomplexa-protozoan pathogen that causes gastroenteritis and diarrhoea in mammals worldwide. The organism is transmitted by ingestion of oocysts, which are shed in faeces, and completes its lifecycle in a single host.^1^ C. parvum is ubiquitous on dairy operations worldwide and is one of the leading causes of diarrhoea in calves on these farms.^2,3^ Here, for the first time, we describe the antibody response in a large group of cows to a recombinant C. parvum oocyst surface protein (rCP15/60) vaccine and the antibody response in calves fed rCP15/60-immune colostrum produced by these vaccinated cows. Results of recent genoty...
Subjects
Medical Subject Headings: animal diseasesparasitic diseases
free text keywords: Immunology, Pathogen, Pharmacotherapy, Feces, Antibody, biology.protein, biology, Bioinformatics, Cryptosporidium, biology.organism_classification, Virology, Vaccination, Cryptosporidium parvum, Colostrum
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publication . Article . Preprint . 2009

Antibody responses to a Cryptosporidium parvum rCP15/60 vaccine

Alexandra J. Burton; Daryl V. Nydam; Gary Jones; Jennifer Zambriski; Thomas C. Linden; Graham Cox; Randy Davis; Alicia Brown; Dwight D. Bowman;