publication . Other literature type . 2012

Kitozan male molekulske mase kao nosač hidrodinamički uravnoteženog sustava za usporenu isporuku ciprofloksacin hidroklorida

Open Access English
  • Published: 01 Jan 2012 Journal: Acta Pharmaceutica, volume 62, issue 2 (issn: 1330-0075, eissn: 1846-9558, Copyright policy)
  • Publisher: Croatian Pharmaceutical Society
Chitosan has become a focus of major interest in recent years due to its excellent biocompatibility, biodegradability and non-toxicity. Although this material has already been extensively investigated in the design of different types of drug delivery systems, it is still little explored for stomach specific drug delivery systems. The objective of the present investigation was to explore the potential of low molecular mass chitosan (LMCH) as carrier for a hydrodynamically balanced system (HBS) for sustained delivery of water soluble drug ciprofloxacin hydrochloride (CP). Various formulations were prepared by physical blending of drug and polymer(s) in varying rat...
free text keywords: low molecular mass chitosan; xanthan gum; ciprofloxacin; hydrodynamically balanced capsules; stomach specific release, kitozan male molekulske mase; ksantan guma; ciprofloksacin; hidrodinamički uravnotežene kapsule; oslobađanje u želucu

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