publication . Other literature type . 2012

Cathepsin D and Its Prognostic Value in Neuroepithelial Brain Tumors

Pigac, Biserka; Dmitrović, Branko; Marić, Svjetlana; Mašić, Silvija;
Open Access English
  • Published: 01 Jan 2012 Journal: Collegium antropologicum, volume 36, issue 1 (issn: 0350-6134, eissn: 1848-9486, Copyright policy)
  • Publisher: Croatian Anthropological Society
Abstract
Expression of Cathepsin D (Cath D) in some primary neuroepithelial brain tumors and its prognostic value were studied. The research included 65 samples of human primary neuroepithelial brain tumors. There were 50 glial tumors (10 diffuse astrocytomas (DA), 15 anaplastic astrocytomas (AA), 25 glioblastomas (GB), 15 embryonic tumors (15 medulloblastomas (MB) as well as 5 samples of normal brain tissue. Immunohistochemical method was applied to monitor diffuse positive reaction in the cytoplasm of brain tumor cells, endothelial cells and tumor stromal cells and showed diffuse positive reaction for Cath D in the cytoplasm of brain tumor cells, endothelial cells and ...
Subjects
free text keywords: cathepsin D; prognostic value; glioma; medulloblastoma
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