publication . Other literature type . 1995

Physiological Characteristics of Some Monoamine Metabolites in Cat Cerebrospinal Fluid

Orešković, Darko; Sanković, Mauricio; Fröbea, Ana; Klarica, Marijan;
Open Access English
  • Published: 01 Jan 1995 Journal: Croatica Chemica Acta, volume 68, issue 3 (issn: 0011-1643, eissn: 1334-417X, Copyright policy)
  • Publisher: Croatian Chemical Society
The concentrations of main metabolites of serotonin and dopamine, 5-hydroxyindoleacetic acid and homovanillic acid, respectively, were measured in cisternal cerebrospinal fluid of cats by high performance liquid chromatography with an electrochemical detector. Higher concentrations of homovanillic acid and a wide interindividual oscillation for both parameters have been found. However, samples collected at four different time intervals showed stabile intraindividual concentrations of the metabolites. The existence of a concentration gradient of both parameters inside the cat cerebrospinal fluid system was confirmed in experiments with a provoked artificial flow ...
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