publication . Other literature type . 2005

Evaluacija Albizia zygia gume kao veziva u tabletama

ODEKU, OLUWATOYIN A.;
Open Access English
  • Published: 01 Jan 2005 Journal: Acta Pharmaceutica, volume 55, issue 3 (issn: 1330-0075, eissn: 1846-9558, Copyright policy)
  • Publisher: Croatian Pharmaceutical Society
Abstract
Albizia guma je evaluirana kao vezivo u tabletama i uspoređivana sa želatinom BP. Svojstva stlačivosti analizirana su mjerenjem gustoće i uporabom Heckelove i Kawakitine jednadžbe, dok su mehanička svojstva tableta evaluirana mjerenjem lomljivosti. Sposobnost oslobađanja lijeka iz tableta procijenjena je mjereći vrijeme dezintegracije i otapanja. Pripravci s Albizia gumom kao vezivom manje se plastično deformiraju uslijed tlaka kompresije nego pripravci sa želatinom. Jačina loma, vrijeme dezintegracije i otapanja povećalo se s povećanjem udjela veziva, dok se lomlljivost smanjila. Tablete s Albizia gumom imaju bolja mehanička svojstva i dulje vrijeme dezintegrac...
Subjects
free text keywords: Albizia gum; gelatin; Heckel equation; Kawakita equation; mechanical properties; drug release, Albizia guma; želatina; Heckelova jednadžba; Kawakita jednadžba; mehanička svojstva; oslobađanje lijeka
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