publication . Article . Other literature type . 2014

Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men.

Karlo Golubić; Anton Šmalcelj; Jadranka Sertić; Ljiljana Juričić;
Open Access
  • Published: 01 Feb 2014
  • Publisher: Medicinska naklada
  • Country: Croatia
Abstract
Aim To determine the association between the number of thymine-adenine (TA)n dinucleotide repeats in the promoter region of the gene coding for the estrogen receptor alpha (ESR1) and the prevalence of lone atrial fibrillation (AF) in men. Methods We conducted a case-control study involving 89 men with lone AF and 166 healthy male controls. The ESR1 genotype was established by polymerase chain reaction and capillary electrophoresis. To assess the association of ESR1 genotype with AF, logistic regression models were built with AF as outcome. Results Men with lone AF had significantly greater number of (TA)n repeats of single alleles than controls (mean ± standard ...
Subjects
free text keywords: /, Clinical Science, General Medicine, Gene, Genotype, Allele, Atrial fibrillation, medicine.disease, medicine, Genetics, Case-control study, Estrogen receptor alpha, business.industry, business, Endocrinology, medicine.medical_specialty, Internal medicine, Polymorphism (computer science), Promoter
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publication . Article . Other literature type . 2014

Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men.

Karlo Golubić; Anton Šmalcelj; Jadranka Sertić; Ljiljana Juričić;