publication . Other literature type . Article . 2016

Zoonotic trypanosomes in South East Asia : attempts to control Trypanosoma lewisi using human and animal trypanocidal drugs

Marc Desquesnes; Sarawut Yangtara; Pawinee Kunphukhieo; Sathaporn Jittapalapong; Stéphane Herder;
Open Access
  • Published: 01 Jan 2016
  • Country: France
Beside typical human trypanosomes responsible of sleeping sickness in Africa and Chagas disease in Latin America, there is a growing number of reported atypical human infections due to Trypanosoma evansi, a livestock parasite, or Trypanosoma lewisi, a rat parasite, especially in Asia. Drugs available for the treatment of T. brucei ssp. in humans are obviously of choice for the control of T. evansi because it is derived from T. brucei. However, concerning T. lewisi, there is an urgent need to determine the efficacy of trypanocidal drugs for the treatment in humans. In a recent study, pentamidine and fexinidazole were shown to have the best efficacy against one st...
Persistent Identifiers
free text keywords: Trypanosoma lewisi, Trypanocidals, Fexinidazole, Trypanosoma evansi, Efficacy, Rats, Suramin, Pentamidine, Eflornitine, Nifurtimox, Benznidazole, Microbiology (medical), Genetics, Ecology, Evolution, Behavior and Systematics, Molecular Biology, Microbiology, Infectious Diseases, 000 - Autres thèmes, L72 - Organismes nuisibles des animaux, L73 - Maladies des animaux, zoonose, Contrôle de maladies, Genre humain, Maladie de l'homme, Rat, Médicament, Efficacité d'utilisation,,,,,,,,,,, Virology, medicine.drug, medicine, Biology, Chagas disease, medicine.disease, Pharmacology, biology.organism_classification, chemistry.chemical_compound, chemistry
Agricultural and Food Sciences
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