publication . Other literature type . Article . 2013

Monitoring of HIV viral load, CD4 cell count, and clinical assessment versus clinical monitoring alone for antiretroviral therapy in low-resource settings (Stratall ANRS 12110/ESTHER): a cost-effectiveness analysis.

Sylvie Boyer; Laura March; Charles Kouanfack; Gabrièle Laborde-Balen; Patricia Marino; Avelin Fobang Aghokeng; Eitel Mpoudi-Ngole; Sinata Koulla-Shiro; Eric Delaporte; Maria Patrizia Carrieri; ...
Open Access
  • Published: 01 Jul 2013
  • Country: United States
Abstract
Summary Background In low-income countries, the use of laboratory monitoring of patients taking antiretroviral therapy (ART) remains controversial in view of persistent resource constraints. The Stratall trial did not show that clinical monitoring alone was non-inferior to laboratory and clinical monitoring in terms of immunological recovery. We aimed to evaluate the costs and cost-effectiveness of the ART monitoring approaches assessed in the Stratall trial. Methods The randomised, controlled, non-inferiority Stratall trial was done in a decentralised setting in Cameroon. Between May 23, 2006, and Jan 31, 2008, ART-naive adults were randomly assigned (1:1) to c...
Subjects
Medical Subject Headings: health care economics and organizations
free text keywords: Infectious Diseases, Immunology, Surgery, medicine.medical_specialty, medicine, Internal medicine, Antiretroviral therapy, Cost-effectiveness analysis, Viral hepatitis, medicine.disease, Viral load, business.industry, business, Cd4 cell
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publication . Other literature type . Article . 2013

Monitoring of HIV viral load, CD4 cell count, and clinical assessment versus clinical monitoring alone for antiretroviral therapy in low-resource settings (Stratall ANRS 12110/ESTHER): a cost-effectiveness analysis.

Sylvie Boyer; Laura March; Charles Kouanfack; Gabrièle Laborde-Balen; Patricia Marino; Avelin Fobang Aghokeng; Eitel Mpoudi-Ngole; Sinata Koulla-Shiro; Eric Delaporte; Maria Patrizia Carrieri; ...