Transcription factor Fos-Related Antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis

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Maurer, B ; Busch, N ; Jüngel, A ; Pileckyte, M ; Gay, R E ; Michel, B A ; Schett, G ; Gay, S ; Distler, J ; Distler, O (2009)

BACKGROUND: -Microvascular damage is one of the first pathological changes in systemic sclerosis. In this study, we investigated the role of Fos-related antigen-2 (Fra-2), a transcription factor of the activator protein-1 family, in the peripheral vasculopathy of system... View more
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