publication . Article . Other literature type . 2016

Passive and active roles of fat-free mass in the control of energy intake and body composition regulation

Dulloo, A G; Jacquet, J; Miles-Chan, J L; Schutz, Y;
Open Access English
  • Published: 14 Dec 2016
  • Country: Switzerland
Abstract
While putative feedback signals arising from adipose tissue are commonly assumed to provide the molecular links between the body’s long-term energy requirements and energy intake, the available evidence suggests that the lean body or fat-free mass (FFM) also plays a role in the drive to eat. A distinction must, however, be made between a ‘passive’ role of FFM in driving energy intake, which is likely to be mediated by ‘energy-sensing’ mechanisms that translate FFM-induced energy requirements to energy intake, and a more ‘active’ role of FFM in the drive to eat through feedback signaling between FFM deficit and energy intake. Consequently, a loss of FFM that resu...
Subjects
Medical Subject Headings: human activities
free text keywords: Nutrient, Endocrinology, medicine.medical_specialty, medicine, Obesity, medicine.disease, Calorie, Fat free mass, Diabetes mellitus, Food science, Composition (visual arts), Vitamin, chemistry.chemical_compound, chemistry, Body mass index, business.industry, business, Internal medicine
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publication . Article . Other literature type . 2016

Passive and active roles of fat-free mass in the control of energy intake and body composition regulation

Dulloo, A G; Jacquet, J; Miles-Chan, J L; Schutz, Y;