publication . Article . 2011

No improvement of survival with reduced- versus high-intensity conditioning for allogeneic stem cell transplants in Ewing tumor patients

Marek Ussowicz;
Open Access English
  • Published: 01 Jan 2011
  • Publisher: Oxford University Press
Abstract
Background: Outcomes of Ewing tumor (ET) patients treated with allogeneic stem cell transplantation (allo-SCT) were compared regarding the use of reduced-intensity conditioning (RIC) and high-intensity conditioning (HIC) regimens as well as human leukocyte antigen (HLA)-matched and HLA-mismatched grafts. Patients and methods: We retrospectively analyzed data of 87 ET patients from the European Group for Blood and Marrow Transplantation, Pediatric Registry for Stem Cell Transplantations, Asia Pacific Blood and Marrow Transplantation and MetaEICESS registries treated with allo-SCT. Fifty patients received RIC (group A) and 37 patients received HIC (group B). Twent...
Subjects
free text keywords: Advanced-stage ewing tumor, Allogeneic stem cell transplantation, Graft versus tumor effect, Haploidentical stem cell transplantation, Reduced/high-intensity conditioning chemotherapy, advanced-stage Ewing tumor, allogeneic stem cell transplantation, graft versus tumor effect, haploidentical stem cell transplantation, reduced, high-intensity conditioning chemotherapy, Oncology, Hematology
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