In vitro pyrogen test for toxic or immunomodulatory drugs

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Daneshian, Mardas; Guenther, Armin; Wendel, Albrecht; Hartung, Thomas; Aulock, Sonja von;
  • Related identifiers: doi: 10.1016/j.jim.2006.04.009
  • Subject: Lipopolysaccharide | Whole blood test | Pyrogen testing | Interleukin-1β
    • ddc: ddc:570
    mesheuropmc: chemical and pharmacologic phenomena | hemic and immune systems

Pyrogenic contaminations of some classes of injectable drugs, e.g. toxic or immunomodulatory as well as false-positive drugs, represent a major risk which cannot yet be excluded due to the limitations of current tests. Here we describe a modification of the In vitro Pyr... View more
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