publication . Doctoral thesis . 2004

In vivo analysis of homing pattern and differentiation potential of cells deriving from embryonic and adult haematopoietic regions

Petrovic, Suzana;
Open Access English
  • Published: 01 Jan 2004
  • Country: Germany
Abstract
The experimental work of this thesis addresses the questions of whether established cell lines injected into murine blastocysts find their way back home and seed preferentially at the site of their origin. Furthermore, can they change their fate and differentiate to unrelated cell types when exposed to the embryonic environment. This survey was based on the fact that different cell lines have different potentials in developing embryos, dependent on their cellular identity. The cell lines used in this survey were AGM region-deriving DAS 104-4, DAS 104-8 cells, yolk sac-deriving YSE cells and bone marrow-deriving FDCP mix cells. These cells were injected into mous...
Subjects
free text keywords: Zelllinie, Zelldifferenzierung, Maus, Embryonalentwicklung, ddc:570
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