publication . Doctoral thesis . 2007

Einfluss repetitiver postprandialer Hyperglykämien auf den kardialen Ischämie- und Reperfusionsschaden

Elbing, Inka Lena;
Open Access German
  • Published: 01 Jan 2007
  • Country: Germany
Abstract
This study demonstrates exacerbated myocardial damage after ischemia/reperfusion injury in animals with repetitive postprandial hyperglycemia that could be prevented by acarbose treatment. The enhanced myocardial injury could not be attributed to altered neutrophil infiltration, but to an increased production of reactive oxygen species. These findings further support starting acarbose treatment already in patients with impaired glucose tolerance before the onset of overt diabetes mellitus.
Subjects
free text keywords: Herzinfarkt, Hyperglykämie, Reperfusion, Acarbose, ddc:610
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