publication . Article . 2004

Treatment of postradical prostatectomy erectile dysfunction with sildenafil in a non selected group of patients

Rubio Briones, J.; Iborra Juan, I.; Dumont Martínez, R.; Casanova Ramón-Borja, J.; Monrós Lliso, J.L.; Ricós Torrent, J.V.; Collado Serra, A.; Solsona Narbón, E.;
Open Access Spanish
  • Published: 01 Sep 2004
  • Publisher: Asociación Española de Urología
Abstract
FUNDAMENTO: Conocer la disfunción eréctil (DE) tras prostatectomía radical en un grupo no seleccionado de pacientes y su respuesta al sildenafilo. MÉTODOS: Incluimos a nuestros pacientes operados entre 1998 y 2001. Los pacientes rellenaron una modificación del IIEF (mIIEF) antes de la PR. Probamos sildenafilo a dosis de 100 mg en 3 periodos diferentes: 3-6, 12 y 18-24 meses tras la PR. En caso de respuesta completa volvieron a rellenar el mIIEF. RESULTADOS: La edad media fue de 62,8 años y el seguimiento medio de 31,7 meses. Sólo 111 (62%) del total de pacientes operados quisieron tratamiento y tan solo 90 tomaron sildenafilo en el régimen propuesto; 27 (30%), 1...
Subjects
free text keywords: Prostatectomía radical, Sildenafilo, Radical prostatectomy, Impotence, Sildenafil, Impotencia

1. Kao TC, Cruess DF, Garner D, Foley J, Seay T, Fiderichs P et al. Multicenter patient self-reporting questionnnaire on impotence. Comment J Urol 2000;163:870-878.

2. Carson CC, Burnett AL, Levine LA, Nehra A. The efficacy of sildenafil citrate (Viagra) in clinical populations. An update. Urology 2002;60(Supplement 2B):12-27.

3. Zagaja GP, Mhoon DA, Aikens JE, Brendler CB. Sildenafil in the treatment of erectile dysfunction after radical prostatectomy. Urology 2000;56(4):631-634.

4. Zippe C, Kdeia AW, Kdeia K et al. Treatment of erectile dysfunction following radical prostatectomy with sildenafil citrate (Viagra). Urology 1998;52:963-966.

5. NIH consensus development on impotence. JAMA 1993; 270:83.

6. Rosen RC, Riley A, Wagner G, Osterloh IH, Kipratrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology 1997;49(6):822-830.

7. Montorsi F, Guazzoni G, Strambi LF, Da Pozzo LF, Nava L, Barbieri L, Rigatti P, Pizzini G, Miani A. Recovery of spontaneous erectile function after nerve-sparing radical retropubical prostatectomy with and without early intracavernous injections of alprostadil: results of a prospective, randomized trial. J Urol 1997;158:1408-1410.

8. Padma-Nathan H, Mc Coullough AR, Giuliano F, Toler SM, Wohlhuter C, Shpilsky AB. Postoperative nightly administration of sildenafil citrate significantly improves the return of normal spontaneous erectile function after bilateral nerve-sparing radical prostatectomy. (Abstract 1402). J Urol 2003;169(4):375.

19. Zippe CD, Jhaveri FM, Klein EA, Kdeia S, Pasqualotto FF, Kdeia A, Agarwal A, Montague AK, Lakin MM. Role of viagra after radical prostatectomy. Urology 2000;55(2):241- 247.

10. Mauleman EJH, Mulders PFA. Erectile function after radical prostatectomy: a review. Eur Urol 2002;43:95- 100.

11. Begg CB, Rideel ER, Bach PB, Kattan MW, Schag D, Warren JL, Scardino PT. Variations in morbidity after radical prostatectomy. New England J MDE 2002;346:1138- 1143.

12. Martín Morales A, Sánchez Cruz JJ, Sáenz De Tejada I, Rodríguez Vela L, Jiménez Cruz JF, Burgos Rodríguez R. Prevalence and independent risk factors for erectile dysfunction in Spain: results of the Epidemiología de la Disfunción Eréctil Masculina Study. J Urol 2001;166(2): 569-575.

13. McCulloough AR, Barada JH, Fawzy A, Guay AT, Hatzichristou D. Achieving treatment optimization with sildenafil citrate (Viagra) in patients with erectile dysfunction. Urology 2000;60(Supplement 2B):28-38.

14. Brock G, Taylor T, Seger M, Vardenafil Prospect Group. Efficacy and tolerability of vardenafil in men with erectile dysfunction following radical prostatectomy. (Abstract 598) Eur Urol 2002;1(suppl 1):152.

Abstract
FUNDAMENTO: Conocer la disfunción eréctil (DE) tras prostatectomía radical en un grupo no seleccionado de pacientes y su respuesta al sildenafilo. MÉTODOS: Incluimos a nuestros pacientes operados entre 1998 y 2001. Los pacientes rellenaron una modificación del IIEF (mIIEF) antes de la PR. Probamos sildenafilo a dosis de 100 mg en 3 periodos diferentes: 3-6, 12 y 18-24 meses tras la PR. En caso de respuesta completa volvieron a rellenar el mIIEF. RESULTADOS: La edad media fue de 62,8 años y el seguimiento medio de 31,7 meses. Sólo 111 (62%) del total de pacientes operados quisieron tratamiento y tan solo 90 tomaron sildenafilo en el régimen propuesto; 27 (30%), 1...
Subjects
free text keywords: Prostatectomía radical, Sildenafilo, Radical prostatectomy, Impotence, Sildenafil, Impotencia

1. Kao TC, Cruess DF, Garner D, Foley J, Seay T, Fiderichs P et al. Multicenter patient self-reporting questionnnaire on impotence. Comment J Urol 2000;163:870-878.

2. Carson CC, Burnett AL, Levine LA, Nehra A. The efficacy of sildenafil citrate (Viagra) in clinical populations. An update. Urology 2002;60(Supplement 2B):12-27.

3. Zagaja GP, Mhoon DA, Aikens JE, Brendler CB. Sildenafil in the treatment of erectile dysfunction after radical prostatectomy. Urology 2000;56(4):631-634.

4. Zippe C, Kdeia AW, Kdeia K et al. Treatment of erectile dysfunction following radical prostatectomy with sildenafil citrate (Viagra). Urology 1998;52:963-966.

5. NIH consensus development on impotence. JAMA 1993; 270:83.

6. Rosen RC, Riley A, Wagner G, Osterloh IH, Kipratrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology 1997;49(6):822-830.

7. Montorsi F, Guazzoni G, Strambi LF, Da Pozzo LF, Nava L, Barbieri L, Rigatti P, Pizzini G, Miani A. Recovery of spontaneous erectile function after nerve-sparing radical retropubical prostatectomy with and without early intracavernous injections of alprostadil: results of a prospective, randomized trial. J Urol 1997;158:1408-1410.

8. Padma-Nathan H, Mc Coullough AR, Giuliano F, Toler SM, Wohlhuter C, Shpilsky AB. Postoperative nightly administration of sildenafil citrate significantly improves the return of normal spontaneous erectile function after bilateral nerve-sparing radical prostatectomy. (Abstract 1402). J Urol 2003;169(4):375.

19. Zippe CD, Jhaveri FM, Klein EA, Kdeia S, Pasqualotto FF, Kdeia A, Agarwal A, Montague AK, Lakin MM. Role of viagra after radical prostatectomy. Urology 2000;55(2):241- 247.

10. Mauleman EJH, Mulders PFA. Erectile function after radical prostatectomy: a review. Eur Urol 2002;43:95- 100.

11. Begg CB, Rideel ER, Bach PB, Kattan MW, Schag D, Warren JL, Scardino PT. Variations in morbidity after radical prostatectomy. New England J MDE 2002;346:1138- 1143.

12. Martín Morales A, Sánchez Cruz JJ, Sáenz De Tejada I, Rodríguez Vela L, Jiménez Cruz JF, Burgos Rodríguez R. Prevalence and independent risk factors for erectile dysfunction in Spain: results of the Epidemiología de la Disfunción Eréctil Masculina Study. J Urol 2001;166(2): 569-575.

13. McCulloough AR, Barada JH, Fawzy A, Guay AT, Hatzichristou D. Achieving treatment optimization with sildenafil citrate (Viagra) in patients with erectile dysfunction. Urology 2000;60(Supplement 2B):28-38.

14. Brock G, Taylor T, Seger M, Vardenafil Prospect Group. Efficacy and tolerability of vardenafil in men with erectile dysfunction following radical prostatectomy. (Abstract 598) Eur Urol 2002;1(suppl 1):152.

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