publication . Article . 2015

Perfil de ácidos grasos de hígados de ratones alimentados con una dieta cetogénica basada en triheptanoína

Meloi, Ingrid Sofia Vieira de; Ataidei, Terezinha da Rocha; Oliveirai, Suzana Lima de; Bezerra Buenoi, Nassib; Freitasi, Johnnatan Duarte de; Sant'Anai, Antônio Euzébio Goulart;
Open Access English
  • Published: 01 Jul 2015
  • Publisher: Grupo Arán
Abstract
Objective: the aim of this study was to evaluate the influence of consumption of a ketogenic diet supplemented with triheptanoin, a medium-chain anaplerotic triacylglycerol, on the liver fatty acid profile of Wistar rats. Methods: three groups of male Wistar rats (n = 10) were submitted to an AIN-93 control diet, a triheptanoin- based ketogenic diet, or a soybean oil-based ketogenic diet for 60 days. Excised livers were subjected to lipid extraction and methylation to obtain fatty acids methyl esters, which were subjected to gas chromatography- mass spectrometry. Results and discussion: compared to the rats fed the control diet, those fed ketogenic diets showed ...
Subjects
free text keywords: Fatty acid profile, Ketogenic diet, Medium-chain triacylglycerols, Trienantin, Ratones Wistar, Triheptanoína, Ácidos grasos
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