publication . Article . 2013

Effect of hydroalcoholic extract of Zingiber officinale Roscoe (Ginger) in the model of hepatotoxicity in rats

Gómez-Rodríguez, Banely Trinidad; Cortés Suárez, Saúl; Izquierdo-Sánchez, Teresa;
Open Access Spanish
  • Published: 01 Sep 2013
  • Publisher: ECIMED
Abstract
Introducción: el rizoma de Zingiber officinale Roscoe (jengibre) familia Zingiberaceae, presenta actividad antioxidante como atrapador de radicales libres y de protección en lipoperoxidación en modelos in vivo e in vitro, debido a sus principales compuestos bioactivos. Objetivo: evaluar el efecto del extracto hidroalcohólico obtenido de Zingiber officinalis en el modelo de hepatotoxicidad por sobredosis de acetaminofén en ratas. Métodos: se preparó un extracto hidroalcohólico del rizoma fresco de Zingiber officinalis. Se utilizaron 42 ratas Wistar, albinas, macho (180-200 g de peso) y se distribuyeron aleatoriamente en 7 grupos (n= 6); 4 grupos fueron administra...
Subjects
free text keywords: extracto hidroalcohólico, paracetamol, actividad antioxidante, actividad hepatoprotectora, jengibre, Zingiber officinale, hydroalcoholic extract, paracetamol overdose, antioxidative activity, hepatoprotective activity, ginger
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