publication . Article . 2016

Efeito do estresse pré-natal na regulação da inflamação alérgica pulmonar no modelo murino de asma experimental

Gonçalves, Vagner; Ligeiro de Oliveira, Ana Paula; Kieling, Karin; Cruz Ochoa, Natalia Andrea; Ochoa Amaya, Julieta E; Cruz-Casallas, Pablo Emilio; Bernardi, Maria Martha;
Open Access Portuguese
  • Published: 01 Jul 2016
  • Publisher: Instituto de Investigaciones de la Orinoquia Colombiana
Abstract
Devido ao seu rápido crescimento, o feto é particularmente vulnerável a insultos e modificações no millieu hormonal. Este fato sugere que situações adversas experimentadas pela mãe grávida podem alterar o desenvolvimento e a saúde da prole, explicado principalmente pela permeabilidade da barreira placentária a diversos hormônios e substâncias. O objetivo deste trabalho foi estudar o efeito do estresse pré-natal na regulação da inflamação alérgica pulmonar, empregando o modelo murino de asma experimental. Para este propósito foram utilizadas camundongas virgens da linhagem Swiss, com 50 dias de idade. Foi empregado o modelo de choque nas patas para promover o est...
Subjects
free text keywords: Neuroimunomodulação, estresse pré-natal, asma, modelo murino, Neuroimunomodulación, estrés prenatal, neuroimmunomodulation, prenatal stress, asthma, Bronchoalveolar lavage, medicine.diagnostic_test, medicine, Allergic inflammation, Sensitization, medicine.anatomical_structure, Immunology, Fetus, Internal medicine, medicine.medical_specialty, Allergic response, medicine.disease_cause, Inflammation, medicine.symptom, Endocrinology, business.industry, business, Offspring
Related Organizations
55 references, page 1 of 4

Ader R, Cohen N, Felten D. Psychoneuroimmunology: interactions system and the immune system. The Lancet. 1995;345: 99-103. [OpenAIRE]

Berkenbosh F, Wolvers D, Derijk R. Stress exposure and immunization Radioimmunoassays (RIAs) CRF antiserum protocol and. Journal of Steroidal Biochemistry and Molecular Biology. 1991;40(4): 639-647.

Biondi M, Zannino LG. Psychological Stress, Neuroimmunomodulation, and Susceptibility to Infectious Diseases in Animals and Man: A Review. Psychotherapy and Psychosomatics. 1997;66(1):3-26.

Boulet LP, FitzGerald JM, Reddel HK. The revised 2014 GINA strategy report: opportunities for change. Current opinion in pulmonary medicine. 2015;21(1): 1-7.

Chen E, Miller GE. Stress and inflammation in exacerbations of asthma. Brain, Behavior, and Immunity. 2007;21(8):993-999.

Choy DF, Choy DF, Hart KM, Borthwick LA, Shikotra A, Nagarkar DR, et al. TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma. 2015;7(301):301-.

Dhabhar FS, McEwen BS. Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: a potential role for leukocyte trafficking. Brain, behavior and immunity. 1997;11(4):286-306. [OpenAIRE]

Entringer S, Buss C, Wadhwa PD. Prenatal stress, development, health and disease risk: A psychobiological perspective-2015 Curt Richter Award Paper. Psychoneuroendocrinology. 2015;62:366-375. [OpenAIRE]

Felicio LF, Florio JC, Sider LH, Cruz-Casallas PE, Bridges RS. Reproductive experience increases striatal and hypothalamic dopamine levels in pregnant rats. Brain Research Bulletin, 1996;40(4):253-256.

Fonseca ESM, Palermo-Neto J. 2005. Participação do sistema opioidérgico e dos glicocorticóides nas alterações comportamentais. Universidade de São Paulo.

Fonseca ESM, Massoco CO, Palermo-Neto J. Effects of prenatal stress on stress-induced changes in behavior and macrophage activity of mice. Stress. 2002;124(5):954-960. [OpenAIRE]

Gerardin DCC, Pereira OC, Kempinas WG, Florio JC, Moreira EG, Bernardi MM. Sexual behavior, neuroendocrine, and neurochemical aspects in male rats exposed prenatally to stress. Physiology and Behavior. 2005; 84(1):97-104.

Gitau R, Cameron A, Fisk NM, Glover V. Fetal exposure to maternal cortisol. The Lancet. 1998;352(9129):707-708. [OpenAIRE]

Glavin GB, Paré WP, Sandbak T, Bakke HK, Murison R. Restraint stress in biomedical research: An update. Neuroscience & Biobehavioral Reviews. 1994;18(2):223-249.

Glover V, O'Connor TG, O'Donnell K. Prenatal stress and the programming of the HPA axis. Neuroscience and Biobehavioral Reviews. 2010;35(1):17-22.

55 references, page 1 of 4
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue
publication . Article . 2016

Efeito do estresse pré-natal na regulação da inflamação alérgica pulmonar no modelo murino de asma experimental

Gonçalves, Vagner; Ligeiro de Oliveira, Ana Paula; Kieling, Karin; Cruz Ochoa, Natalia Andrea; Ochoa Amaya, Julieta E; Cruz-Casallas, Pablo Emilio; Bernardi, Maria Martha;