publication . Article . 2015

Localización de los Receptores Cannabinoides 1 (CB1) en Glándulas Salivales Submandibulares y Sublinguales de Ratones Durante el Desarrollo Postnatal

Hipkaeo, Wiphawi; Watanabe, Masahiko; Kondo, Hisatake;
Open Access English
  • Published: 01 Jun 2015
  • Publisher: Sociedad Chilena de Anatomía
Abstract
In view of the fact that human marijuana users often show dry mouth symptom, the present study was attempted to examine the localization of CB1, which was originally identified in brain, in the submandibular and sublingual salivary glands of postnatal developing male mice by immunohistochemistry. In submandibular gland, CB1-immunoreactivity was positive in a majority of acinar cells in forms of granular appearance in their apical cytoplasm, while it was negative in the ducts at newborn stage. The immunoreactivity decreased in the acinar cells at P1W and no immunoreactivity was detected in the acinar cells at P3W and thereafter. The immunoreactivity was positive ...
Subjects
mesheuropmc: stomatognathic system
free text keywords: Glándula submandibular, Sublingual gland, Ratón postnatal, Receptores de cannabinoides 1, Inmunohistoquímica, Glándula sublingual, Cannabinoid receptor 1, Immunohistochemistry, Postnatal mice, Submandibular gland
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