publication . Article . 2012

Evaluación de la globulina transportadora de hormonas esteroidales (SHBG) durante el embarazo como factor predictor de pre-eclampsia y restricción del crecimiento intrauterino

Valdés R, Enrique; Lattes A, Karina; Muñoz S, Hernán; Ángel Cumsille, Miguel;
Open Access Spanish
  • Published: 01 May 2012
  • Publisher: Sociedad Médica de Santiago
Background: Sex-Hormone Binding Globulin (SHBG) may be associated to Pre-eclampsia (PE) and Fetal Growth Restriction (RCIU). Aim: To determine if maternal serum SHBG concentrations during the first and second trimesters are predictive biomarkers of Pre-eclampsia and RCIU. Patients and Methods: Prospective cohort study carried out in the Fetal Medicine Unit, Universidad de Chile Clinical Hospital between January, 2005 and December, 2006. Blood samples were obtained from unselectedpregnant women during routine 11-14 week and 22-25 week ultrasound examinations, conforming two different study groups. Posteriorly, serum SHBG concentrations were determined in women wh...
Medical Subject Headings: reproductive and urinary physiology
free text keywords: Fetal development, Pre-eclampsia, Sex hormone-binding globulin
28 references, page 1 of 2

1. Khong TY, De Wolf F, Robertson WB, Brosens I. Inadequate maternal vascular response to placentation in pregnancies complicated by preeclampsia and by small for gestational age infants. Br J Obstet Gynaecol 1986; 93: 1049-59. [OpenAIRE]

2. Roberts JM, Redman CWG. Pre-eclampsia: More than pregnancy induced hypertension. Lancet 1993; 341: 1447-54.

3. Campbell S, Pearce JM, Hackett G, Cohen-Overbeek T, Hernández C. Cualitative asssessment of uteroplacental blood flow: early screening test for high-risk pregnancies. Obstet Gynecol 1986; 68: 649-53.

4. Sibai BM. Prevention of preeclampsia: a big disappointment. Am J Obstet Gynecol 1998; 179: 1275-8.

5. Arngrimsson R, Björnsson S, Geirsson RT, Björnsson H, Walker JJ, Snaedal G. Genetic and familial predisposition to eclampsia and preeclampsia in a definited population. Br J Obstet Gynecol 1990; 97: 762-9. [OpenAIRE]

6. Robillard PY, Hulsey TC, Perianin J, Janky E, Miri EH, Papiernik E. Association of pregnancy induced hypertention with duration of sexual cohabitation before conception. Lancet 1994; 344: 973-5.

7. Redman CW, Saks GP, Sargent IL. Preeclampsia and excessive maternal inflammatory responsive to pregnancy. Am J Obstet Gynecol 1999; 180: 499-506.

8. Barker DJP. Programming the baby. In mothers, babies and disease in later life. BMJ Publishing Group, London pp. 14-36.

9. Campbell S, Pearce JM, Hackett G, Cohen-Overbeek T, Hernández C. Cualitative asssessment of uteroplacental blood flow: early screening test for high-risk pregnancies. Obstet Gynecol 1986; 68 (5): 649-53.

10. Pilalis A, Souka AP, Antsaklis P, Daskalakis G, Papantoniou N, Mesogitis S, et al. Screening for pre-eclampsia and fetal growth restriction by uterine artery Doppler and PAPP-A at 11-14 weeks' gestation. Ultrasound Obstet Gynecol 2007; 29 (2): 135-40. [OpenAIRE]

11. Ciaraldi TP, Kettel M, El-Roeiy A, Madar Z, Reichart D, Yen SCC, et al. Mechanisms of cellular insulin resistance in human pregnancy. Am J Obstet Gynecol 1994; 170 (2): 635-41.

12. Timar O, Sestier F, Levy E. Metabolic Síndrome X: a review. Can J Cardiol 2000; 16: 779-89.

13. Kirwan JP, Huston-Presley L, Kalhan SC, Catalano PM. Clinically useful estimates of insulin sensitivity during pregnancy: validation studies in women with normal glucose tolerance and gestational diabetes mellitus. Diabetes Care 2001; 24 (9): 1602-07. [OpenAIRE]

14. Catalano PM, Tyzbir ED, Roman NM, Amini SM, Simus EAH. Longitudinal changes insulin release and insulin resistance in nonobese pregnant women. Am J Obst Gynec 1991; 165: 1667-72. [OpenAIRE]

15. Barbieri RL. Endocrine disorders in pregnancy. 1999. Eds Reproducitve endocrinology. Philadelphia. Pa: WB Saunders Co.

28 references, page 1 of 2
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue