publication . Article . 2011

Effect of Chilean Propolis on Glucose Metabolism in Diabetic Mice

Alejandro Pacheco; Julio B Daleprane; Vanessa S Freitas; Simone Ferderbar; Sandro Hirabara; Alejandro Cuevas; Nicolás Saavedra; Rui Curi; Dulcineia S. P Abdalla; Luis A Salazar;
Open Access Spanish
  • Published: 01 Sep 2011
  • Publisher: Sociedad Chilena de Anatomía
Abstract
En el presente estudio se evaluó el efecto del propóleos sobre el metabolismo de la glucosa en ratones C57/BL-6 con diabetes mellitus tipo 2 inducida por dieta alta en grasa. Se midieron los cambios en las concentraciones séricas de lípidos, glucosa e insulina, y el efecto sobre la captación de 2-deoxi-[2,6-3H]-D-glucosa, síntesis de [14C]-glicógeno y descarboxilación de [U-14C]-D-glucosa inducida por insulina en músculo aislado. Los resultados muestran que en ratones diabéticos, el tratamiento con propóleos (150 mg/kg/día) reduce los niveles de insulina e índice HOMA (P<0.05). También disminuyó la obesidad abdominal de estos animales (P<0.05). Por otro lado, no...
Subjects
free text keywords: Propóleos, Ratones Diabéticos, Polifenoles, Glucosa, Propolis, Diabetic Mice, Polyphenols, Glucose, Anatomy, Gynecology, medicine.medical_specialty, medicine, business.industry, business
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publication . Article . 2011

Effect of Chilean Propolis on Glucose Metabolism in Diabetic Mice

Alejandro Pacheco; Julio B Daleprane; Vanessa S Freitas; Simone Ferderbar; Sandro Hirabara; Alejandro Cuevas; Nicolás Saavedra; Rui Curi; Dulcineia S. P Abdalla; Luis A Salazar;