publication . Article . Report . 2014

Brown tumors of the femur and pelvis secondary to a parathyroid carcinoma: report of one case.

Radulescu,Dan; Chis,Bogdan; Donca,Valer; Münteanu,Valentin;
Open Access
  • Published: 01 Jul 2014 Journal: Revista médica de Chile, volume 142, pages 919-923 (issn: 0034-9887, Copyright policy)
  • Publisher: SciELO Comision Nacional de Investigacion Cientifica Y Tecnologica (CONICYT)
Abstract
Brown tumors result from excess osteoclast activity and consist of collections of osteoclasts intermixed with fibrous tissue and poorly mineralized woven bone. They are secondary to hyperparathyroidism (HPT). Their incidence is higher in primary than in secondary hyperparathyroidism. We report a 69 years-old male, admitted in a state of confusion, lethargy and bedridden, with a pathological fracture of the femur caused by a brown tumor. The laboratory examination revealed a hypercalcemia (8.85 mEq/L), with high levels of ionized Ca (5.48mEq/L), serum alkaline phosphatases (416 U/L) and serum parathormone (120 pg/mL). Ultrasound examination of the neck showed a l...
Subjects
free text keywords: Hypercalcemia, Hyperparathyroidism, Parathyroid neoplasms
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