publication . Patent . 2009

Method and device for thermal control of biological and chemical reactions using magnetic particles or magnetic beads and variable magnetic fields

Zilch, C.; Gerdes, W.; Bauer, J.; Holschuh, K.;
Open Access English
  • Published: 01 Jan 2009
  • Country: Germany
Abstract
The invention relates to a method for the thermal control of at least one temperature-dependent enzymatic reaction in the presence of magnetic particles, particularly nanoparticles, or magnetic beads, in vitro by heating the magnetic beads or magnetic particles to at least one defined target temperature using alternating magnetic fields. The thermally controllable enzymatic reaction carried out with the method according to the invention is preferably a PCR reaction or another reaction for elongating or multiplying nucleic acids, including DNA, RNA, or hybrids or derivatives thereof, which takes place directly on the functionalized magnetic beads. Further aspects...
Subjects
arXiv: Quantitative Biology::Biomolecules
Medical Subject Headings: equipment and supplieshuman activitieshumanities
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Digital Humanities and Cultural Heritage
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